About This Test
Tumor necrosis factor (TNF)-alpha is expressed primarily by activated monocytes as part of the innate immune response to various microbes, gram-negative bacteria in particular. Its function is to recruit other leukocytes to the site of infection and to stimulate their activation. TNF-alpha also has some systemic effects, including induction of fever through action on the hypothalamus. In cases of severe gram-negative bacterial infection, Septic shock can occur characterized by hypotension, disseminated intravascular coagulation, tachycardia & increased respiration and can be fatal. Dysregulation of TNF-alpha expression is thought to be a critical pathogenic mechanism in numerous autoimmune diseases, including Inflammatory bowel disease (IBD), Rheumatoid arthritis (RA) and Ankylosing spondylitis (AS). TNF-alpha is used for the evaluation of patients with suspected systemic infection, particularly caused by gram-negative bacteria & for the evaluation of patients with suspected chronic inflammatory disorders.
Test Parameters (1)
- TUMOR NECROSIS FACTOR (TNF) ALPHA; TNF-a
Home Collection
✓ Available
Reports Available In
3 Days
Frequently Asked Questions
Outsourced test are being done from Dr. Lal Path Lab. Charges and reporting time is same as of Dr. Lal Path Labs.
No special preparation required
The TNF-Alpha (Tumor Necrosis Factor-α) test is important because it helps assess inflammation, immune system activation, and disease activity in a wide range of autoimmune, inflammatory, infectious, and metabolic disorders.
TAT Policy
The Turnaround Time (TAT) depends on the following factors:
- Registration date and time
- Type of scan or test
- Scan time or sample collection time
In uncommon circumstances, TAT may be delayed due to test complexity or reasons beyond our control. You will be informed of the estimated TAT at the time of registration.
