About Saral Diagnostics
We started in 1984 under professional guidance of Dr. Ravi Gupta, MD Radio diagnosis from Delhi University with a vision and motto to serve and provide latest medical investigations.
We are a multimodality Diagnostic centre to serve all your diagnostic need under one roof. At Delhi we are spread over more than 25000 sq. ft. and at Noida we are spread over more than 11,000 sq. ft.We are the first NABH Accredited Diagnostic centre in the country. We have all the major government panels.
What is PET-CT
Positron emission tomography–computed tomography (PET-CT) is a nuclear medicine technique which combines, in a single gantry, a positron emission tomography scanner and an x-ray computed tomography scanner, to acquire sequential images from both devices in the same session, which are combined into a single superposed image.
Principle of PET CT (How PET-CT works)
Tumour cells take up glucose under aerobic conditions constitutes the basis for the detection and staging of human cancers with 18F-fluorodeoxyglucose (FDG) and positron emission tomography (PET). 18F-FDG is a structural analogue of 2-deoxyglucose and is used as a tracer of glucose metabolism.Positron Emission Tomography (PET) detects and measures glucose metabolism within the body. In cancers and certain diseases of the heart and brain, the metabolism of glucose may be abnormal.
What is Digital PET-CT
Digital PET-CT imaging is the latest advancement in PET- CT (providing high definition PET images and offering higher sensitivity and higher diagnostic performance). Digital PET-CT imaging is transforming cancer diagnostics with precision, detecting even the smallest lesions missed by conventional imaging techniques, including the analogue PET CT, leading to personalized treatment options and improved patient outcomes. Smallest lesion detectability can change the patient management and improving outcomes in oncological and non-oncological diseases. AI Based reconstruction gives best image quality in lesser injected dose leading to significantly less radiation burden to the patient.
Advantages of digital PET-CT
- Better - image quality, Industries’ best clinical reolution of 1.4 mm.
- Clearer - Crystal clear image quality, Sharper, superior images for accurate disease diagnosis and staging
- Faster - Whole body scanning in just 6-8 min vs. 15-20 min
- Safer - Significantly less radiation to the patient, Digital technology, AI Based reconstruction, Digital Motion correction & Digital Self gating feature avoid repetition of scan leading to less radiation to the patient
- Comfortable - Accommodates patients of all sizes (Upto 250 kg body weight), Compact Gantry Width , Unique in-bore light feature leading to less claustrophobia
- Inclusive - Beyond cancer, digital PET-CT proves valuable in neurology and cardiology, offering precise diagnosis, staging, and treatment evaluation, particularly in early-stage cancer, where tumor size matters most.
Advantages of PET-CT over other imaging modalities
- EARLY detection of disease before appearance of anatomical changes.
- ACCURATE staging and restating of cancers.
- SIMULTANEOUS contrast enhanced CT with metabolic information - cost effective way of imaging the whole body in one sitting.
- QUANTIFICATION of tumor metabolism (SUV) before and after treatment.
- Metabolic GRADING of tumors possible - Impacts treatment decisions.
- SAFE for use in patients with chronic kidney disease, metallic implants, pacemakers, etc.
Test details
Whole body FDG PET-CT Scan
Oncology:
To diagnose primary malignancy : early detection (Because PET images biochemical activity, it can accurately characterize a tumor as benign or malignant, thereby avoiding surgical biopsy when the PET scan is negative)
Initial staging of known malignancy : PET-CT is extremely sensitive in determining the full extent of disease, because of whole body combined functional and anatomical imaging. Confirmation of metastatic disease allows the physician and patient to more accurately decide how to proceed with the patient's management.
Treatment response evaluation : The level of tumor metabolism (SUV) is compared on PET scans taken before and after a chemotherapy cycle. A successful response seen on a PET scan frequently precedes alterations in anatomy and would therefore be an earlier indicator of tumor response than that seen with other diagnostic modalities.
Post treatment restaging : Once the desired treatment is completed, PET scan is done to check to find any residual cancer cells in the body, if found immediate second line treatment is started.
Follow up to check recurrences : PET is considered to be the most accurate diagnostic procedure to differentiate tumor recurrences from radiation necrosis or post-surgical changes.
Infections:
In PUO - to localise site of occult infection / inflammation.
Tuberculosis - to assess multi focal involvement and response to treatment
Infected Implants/ grafts
Osteomyelitis
Sarcoidosis
Vasculitis
Irritable bowel disease/ syndrome (IBS)
FDG PET-CT with Triple phase CT
Hepatocellular carcinoma - in cases of raised alphafetoproein with suspicious USG/ CT imaging for HCC. For better diagnosis of liver, adrenal and pancreatic lesions
F18 PSMA PET-CT Scan
PSMA PET-CT is indicated
(1) in men with newly diagnosed prostate cancer who are at risk for metastatic disease, and
(2) men who have previously been treated for their prostate cancer with curative intent (e.g. with surgery and/or radiation) and now have suspected persistent or recurrent disease based on a rising prostate specific antigen (PSA) level in their blood.
F18-NOTANOC PET-CT Scan
F-18 NOTANOC PET-CT scan is a whole-body examination which gives information regarding the site and extent of primary NET and distant metastasis.
A. Common NETs
(i) Pheochromocytoma
(ii) Medullary Ca thyroid
(iii) Insulinoma
B. Other NETs
Carcinoid, neuroblastoma, Gastrinoma, Merkel Cell Carcinoma, Gatric and Large bowel NET, Somatostatinoma, Pancreatic polypeptidoma, Paraganglioma, Gluganoma, Lung NET, MEN, NET of Pitutary etc.
FDG Brain PET Scan
Dementia - PET will help to differentiate different types of dementias - Alzheimer, Fronto temporal, senile dementia - helps in decision making on line of management of dementia
Seizure- To look for epileptic focus
Brain tumor recurrence vs radiation necrosis, differentiate benign to malignant tumour.
F18 - DOPA PET-CT Scan
Will help to differentiate tremors of parkinson Vs non parkinson disorder - help in deciding line of management.
Dementia
Neuroendocrine tumours
Epilepsy
Brain tumours
FDG Cardiac PET Scan
Myocardial viability assessment, to detect hibernating myocardium in post MI patients- help plan treatment protocol - revasularise / medical management
Cardiac sarcoidosis, Myocarditis and infective endocarditis
F18-Choline PET-CT Scan
Most sensitive investigation to localise parathyroid adenoma in case of Primary hyperparathyroidism
More Sensitive than MIBI Parathyroid scan
Better localization of lesion/ multiple lesions
