OUTSOURCE
TPMT (Thiopurine Methyl Transferase) Genotyping N071
Also Known As:
Thiopurine Methyl Transferase
TPMT Genotyping
About This Test
Detection of TPMT genetic variants by genotyping is recommended prior to commencing the treatment of patients with Thiopurine drugs such as Azathioprine, 6-Mercaptopurine and 6-Thioguanine for Acute Lymphoblastic Leukemia & autoimmune disorders like Crohns disease & Rheumatoid arthritis.TPMT is an enzyme which converts these drugs in the body to an active form. Any genetic defect in this enzyme predisposes patients to a heightened risk of drug-induced bone marrow toxicity due to accumulation of unmetabolised drug. Approximately 0.3% of individuals lack TPMT activity while 11% show reduced activity (variants TPMT*2, 3A & 3C). 89% of people have normal activity (variant TPMT*1).
Test Parameters (1)
- TPMT (THIOPURINE METHYL TRANSFERASE) GENOTYPING
Home Collection
✓ Available
Reports Available In
1 Day
Frequently Asked Questions
Outsourced test are being done from Dr. Lal Path Lab. Charges and reporting time is same as of Dr. Lal Path Labs.
Physician prescription is mandatory.
The TPMT (Thiopurine Methyltransferase) Genotyping test is important because it helps predict how a patient will metabolize thiopurine drugs, ensuring safe and effective treatment while preventing serious drug toxicity.
TAT Policy
The Turnaround Time (TAT) depends on the following factors:
- Registration date and time
- Type of scan or test
- Scan time or sample collection time
In uncommon circumstances, TAT may be delayed due to test complexity or reasons beyond our control. You will be informed of the estimated TAT at the time of registration.
