About This Test
p16 expression plays a major role in the evaluation of Cervical Squamous Intraepithelial lesions (SIL) & distinguishing dysplasia from benign mimics. Overexpression is seen in most high risk HPV associated squamous lesions whereas absent / focal weak expression is seen in normal / inflamed / atrophic cervical epithelium. p16 expression has also been seen in non HPV related tumors like High grade serous carcinoma & Atypical uterine smooth muscle tumors like Leiomyosarcomas. Testing of oropharynyngeal squamous cell carcinomas with p16 is also indicated where it serves as an excellent surrogate marker for active HPV.
Test Parameters (1)
- IMMUNOHISTOCHEMISTRY: P16
Home Collection
✗ Not Available
Reports Available In
6 Days
Frequently Asked Questions
Outsourced test are being done from Dr. Lal Path Lab. Charges and reporting time is same as of Dr. Lal Path Labs.
Provide a copy of the Histopathology report.
p16 is a tumor suppressor protein that regulates the cell cycle. Immunohistochemistry for p16 is commonly used to detect abnormal cell proliferation and virus-related cancers, particularly HPV-associated lesions.
TAT Policy
The Turnaround Time (TAT) depends on the following factors:
- Registration date and time
- Type of scan or test
- Scan time or sample collection time
In uncommon circumstances, TAT may be delayed due to test complexity or reasons beyond our control. You will be informed of the estimated TAT at the time of registration.